demographic and clinical characteristics of gastric cancer patients in north of iran, mazandaran province, 2008-2014
Authors
abstract
gastric cancer has been known as a poor prognosis disease with a high degree of mortality. in iran, it has been increased during the previous two decades, especially in northern part of the country. the aim of this study was to determine the demographic and clinical characteristics of gastric cancer in mazandaran province. all patients with gastric cancer diagnosis treated in the imam khomeini educational hospital or touba polyclinic, a university affiliated center, from march 2008 to march 2014 were included. demographic data, the symptoms at the time of presentation, tumor size, type of tumor, lymph node involvement, status in terms of metastatic disease, therapeutic plan and type of chemotherapy regimens were gathered from patients’ medical records. statistical analysis was performed using spss, version 16. totally, 643 patients were investigated. the mean age of patients were 64.34 years and men were more affected than women. “time to relapse” and “time to progression” were 13 and 6.5 months, respectively. the most common initial symptoms at diagnosis were nausea, vomiting and epigastric pain (47.4%). only in 6.3%, the disease was diagnosed at the initial stages. the most common site of involvement was cardia (almost 40%) and antrum (32%). more than 91% of tumors were adenocarcinoma. dcf (docetaxel, cisplatin, 5fu) (43.3%), xeloda (15.2%), dox (docetaxel.oxaliplatin) (13.8%) and ecf (epirubicin.cisplatin.5fu) (9.2%) were the most common used regimens. there was a trend for improved survival with dcf regimen (p=0.08). most gastric cancer patients were referred in the advanced stage or metastatic disease. the demographic characteristics are consistent with other previous reports. dcf regimen may have some advantages over the other chemotherapy regimens.
similar resources
Demographic and clinical characteristics of gastric cancer patients in north of Iran, Mazandaran province, 2008-2014
Gastric cancer has been known as a poor prognosis disease with a high degree of mortality. In Iran, it has been increased during the previous two decades, especially in northern part of the country. The aim of this study was to determine the demographic and clinical characteristics of gastric cancer in Mazandaran province. All patients with gastric cancer diagnosis treated in the Imam Khomeini ...
full textInfertility in Mazandaran province - north of Iran: an etiological study
BACKGROUND The prevalence and etiology of infertility are not similar in different parts of the world. There are only few reports of this topic in Iran. OBJECTIVE This study was conducted to determine the clinical patterns and major causes of infertility in Mazandaran province in north of Iran. MATERIALS AND METHODS The medical records of 3734 consecutive couples attending two infertility c...
full textRelationship between demographic and pathological characteristics on the 5-year survival rate of gastric cancer patients in Tehran province
full text
Characteristics of patients with phenylketonuria in Mazandaran Province, northern, Iran
Background: Phenylketonuria (PKU) is an autosomal recessive disease of Phenylalanine metabolism that brings deficiency of the enzyme Phenylalanine Hydroxylase (PAH). Early diagnosis is very important to prevent complications. This study was designed to describe characteristics of patients with phenylketonuria in Mazandaran Province in northern Iran. Methods: We studied 24 cases suffering from P...
full textRisk factors of breast cancer in north of Iran: a case-control in Mazandaran Province.
INTRODUCTION Breast cancer is the most common cancer among Iranian women. This study aimed to determine risk factors for breast cancer in the north of Iran. METHOD A matched case-control study was conducted in Mazandaran province of Iran in 2004 of 250 biopsy proven cases of breast cancer and 500 neighbor controls that were matched by age within a 3 year period. Statistical analysis was carri...
full textTorque Teno Virus (TTV) Among β-Thalassemia and Haemodialysis Patients in Mazandaran Province (North of Iran)
Torque Teno virus (TTV) is a transfusion transmitted virus that seems to be involved in several complications such as acute respiratory diseases, liver diseases, AIDS, cancer, and autoimmune reactions. In the present study the frequency of TTV was investigated among β- thalassemia (BT) and haemodialysis (HD) patients (high risk patients for TTV) in Mazandaran province, Iran. DNA was extracted f...
full textMy Resources
Save resource for easier access later
Journal title:
pharmaceutical and biomedical researchجلد ۱، شماره ۱، صفحات ۳۲-۳۶
Keywords
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023